Single Photon Emission Computed Tomography

Single Photon Emission Computed Tomography is a radiotracer imaging modality that utilizes single photon (gamma rays) emitting radionuclides such as 99mTc, 123I and 111In. SPECT has spatial resolution comparable to that of Positron Emission Tomography, but significantly lower sensitivity.

Similar to PET, SPECT can also be used for image perfusion and other physiological processes, as well targeting radiolabeled antibodies and peptides. In addition, SPECT can be used to track radiolabeled small molecules and also for cell trafficking studies with directly labeled cells.

The Center for Molecular Imaging is acquiring a SPECT/CT system capable of high-resolution molecular animal imaging.